Articles Researching Barley and Beta-Glucan


Lipids Significantly Reduced by Diets Containing Barley in Moderately Hypercholesterolemic Men
Written By: Behall, K.M., Scholfield, D.J., and Hallfrisch, J. | Found In: Journal of the American College of Nutrition 2004 Published: January 01, 2004

Abstract

Objective: To determine whether barley, as the soluble fiber source, would beneficially
change cardiovascular risk factors. Soluble fiber from oats has been recognized as
beneficial in decreasing blood cholesterol levels. Although barley contains high amounts
of soluble fiber, it is not consumed as extensively as oats.

Methods: Eighteen moderately hypercholesterolemic men (2862 y) consumed a
controlled equilibration diet (Step 1, 30% fat, 55% carbohydrate, 15% protein, < 300 mg
cholesterol) for 2 weeks followed by the diet with about 20% of energy replaced with
brown rice/whole wheat, 1⁄2 barley & 1⁄2 brown rice/whole wheat or barley (< 0.4 g, 3 g
and 6 g added soluble fiber/2800 kcal, respectively) for 5 weeks in a Latin square design.
Fasting blood was drawn twice weekly. Total cholesterol, HDL cholesterol, and
triacylglycerols were measured enzymatically and lipid fractions were measured by
nuclear magnetic resonance spectroscopy.

Results: Compared with prestudy concentrations, total cholesterol (14%, 17%, and 20%,
respectively) and LDL cholesterol (17%, 17%, and 24%, respectively) were significantly
lower (p < 0.0001) after the low, medium, and high-soluble fiber diets. Triacylglycerol
was 6%, 10%, and 16% lower (p = 0.09) whereas HDL cholesterol (9%, 7%, and 18%)
was higher (p < 0.001) after the experimental diets. Total cholesterol and LDL
cholesterol after the high-soluble fiber diet were significantly lower than concentrations
after the low- or medium-soluble fiber diets. Mean LDL particle number significantly
decreased (p = 0.007) and the large LDL cholesterol fraction showed a trend toward
lower concentrations (p = 0.06).

Conclusion: Increasing soluble fiber through consumption of barley in a healthy diet can
reduce cardiovascular risk factors.

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